Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-11-14
1996-12-31
Criares, Theodore J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514428, A61K 3140
Patent
active
055894992
ABSTRACT:
The invention deals with the use of N-(aminoacyl)-amino acids of Formula (I), especially anapril, (2 R, 4 R)-2-(2-hydroxy-phenyl)-3-(3-aminopropionyl)-4-thiazolidine carboxylic acid, and 1-[(2 S)-3-amino-4-methyl-propionyl]-2-proline as dopaminergic active ingredients for increasing central or peripheral blood flow disorders.
REFERENCES:
patent: 4046889 (1977-09-01), Ondetti et al.
patent: 4316906 (1982-02-01), Ondetti
patent: 4374829 (1983-02-01), Harris et al.
C. Hansch (Ed.) Comprehensive Medicinal Chemistry, vol. 2, Pergamon Press, Oxford, 1990, pp. 400 to 404.
The Merck Index, 10. ed., 1983, pp. 1174 to 1175, No. 8039 to 8042.
J. Witzke and H.-J. Gilfrich, Deutsche Apotheker Zeithung 127. Jahrg., NR. 38, 17.09.1987, pp. 103 to 105.
J. Fuchs, et al, "2 Mercaptopropronylglycine . . . Damage", Arzneim-Forsch/Drug Res. 35(11), Nr9 (1985).
H. Yamauchi, et al., "General Pharmacological . . . Rentiapril", Arzneim-Forsch/Drug Res. 37(1), Nr2 (1987).
Toyohazw Takada, et al. "Effects of an Angiotensin . . . Dogs", Short Communications, Japan. J. Pharmacol. 38,227 (1985).
Yoshio Suzuki, et al. "Studies on Mechanisms of Antinephritu Action of SA-446", Japan. J. Pharmacol. 42, 465-475 (1986).
C. Lombardi, et al. Enalapril . . . patients, "Journal of Biological Regulators & Homeostatic Agents," Band 3, Nr 3, Jul.-Sep. 1989, Seiten 128-129, Milano, Italy.
C. Lombardi, et al., "Meicanismi . . . ipofisario", Minerva Medus, Band 81, Nr 9, Sep. 1990 Seiten 587-590, IT.
J. E. F. Reynolds, et al. "Martindale the Extra Pharmacopoeia", Ed. 29, 1989, The Pharmaceutical Press, Seiken 478-480, London, GB.
J. E. F. Reynolds, et al. "Martindale, The Extra Pharmaceopoeia", Ed. 29, 1989, The Pharmaceutical Press, Seiken 493, London, G.B.
W. B. Malarkey, et al. "Angioteusin . . . manner", The Journal of Clinical Endocrinology & Metabolism, Bd 64, Nr 4, Apr. 1987, pp. 713-717, The Endocrins Society.
Angiology, Band 41, NR. 5, May 1990, pp. 377-381, New York, US. I. Saito et al.: "Effect of Captopril On Plasma Prolactin In Hypertension"--Summary: p. 379, Figure 1.
Prolactin, Basic And Clinical Correlates, Band 1, 1985, pp. 53-57, Liviana Press, Padova, IT; C. Denef: "Paracrine Interaction In Anterior Pituitary" --Entire Document.
The Journal of Clinical Endocrinology & Metabolism, Band 64, NR.4, Apr. 1987, pp. 713-717, The Endocrine Society, US: W. B. Malarkey et al.: "Angiotensin II Promotes Prolactin".
"Release From Normal Human Anterior Pituitary Cell Culters in a Calcium-Dependent Manner" 1987.
The Merck Index, Published by Merck & Co Inc, Rahway N.J. Eleventh Edition No. 3521, pp. 557-558 (1989).
Merck Index, 11th Edition, (1989), Merck & Co., Inc., Rahway N.J. p. 8149.
LandOfFree
Dopaminergic agents for the treatment of cerebral and peripheral does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Dopaminergic agents for the treatment of cerebral and peripheral, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dopaminergic agents for the treatment of cerebral and peripheral will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1142457