Dopamine receptor ligands and imaging agents

Details Dopamine receptor ligands and imaging agents Dopamine receptor ligands and imaging agents

1989-04-17

1992-06-16

Stoll, Robert L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

514422, 546126, 548400, 548525, 549354, 549414, 549456, 564161, 564163, 564180, 564181, 564189, A61K 4300, A61K 4902, A61K 3140, C07D49802

Patent

active

051223619

ABSTRACT:
Novel CNS dopamine D-2 receptors, such as the compound 5-iodo-7-N-[(1-ethyl-2-pyrrolidinyl)methyl]carboxamide-2,3-dihydrobenzofur an, are disclosed. These compounds are useful as imaging agents for D-2 receptors in the human brain and exhibit good brain retention and in vivo stability.

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