Dopamine receptor ligands and image agents

Details Dopamine receptor ligands and image agents Dopamine receptor ligands and image agents

1991-12-31

1993-02-16

Stoll, Robert L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

548566, 548567, 564168, 564181, A61K 4902, C07B 5900, C07D20709

Patent

active

051869217

ABSTRACT:
Novel CNS dopamine D-2 receptors, such as the compound 5-iodo-7-N-[(1-ethyl-2-pyrrolidinyl)methyl]carboxamide-2,3-dihydrobenzofur an, are disclosed. These compounds are useful as imaging agents for D-2 receptors in the human brain and exhibit good brain retention and in vivo stability.

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