Dopamine D4 receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514314, 544363, 546175, 546176, A61K 31495, A61K 3147, C07D40106, C07D40306

Patent

active

059454210

ABSTRACT:
This invention relates to compounds that are antagonists of dopamine D4 receptors, to methods of treating psychosis and schizophrenia using a compound that is an antagonist of dopamine D4 receptors, and to pharmaceutically acceptable compositions that contain a dopamine D4 receptor antagonist.

REFERENCES:
patent: 4859670 (1989-08-01), Kampe et al.
patent: 5206366 (1993-04-01), Bowles
patent: 5240919 (1993-08-01), Yous et al.
patent: 5300507 (1994-04-01), Yous et al.
patent: 5322843 (1994-06-01), Yous et al.
patent: 5322849 (1994-06-01), Yous et al.
patent: 5326775 (1994-07-01), Yous et al.
patent: 5386034 (1995-01-01), Yous et al.
patent: 5436348 (1995-07-01), Yous et al.
patent: 5607946 (1997-03-01), Kulagowski et al.
Rao, V.A., et al., "Agents Acting on the Central Nervous System. XIII. Hypotensive Agents," 1970, J Med Chem, 13:3, 516-522.
TenBrink et al., J.Med. Chem.39, pp. 2435-2437. 1996.
Kuroita et al., Chemical Abstracts, vol. 128, No. 61522 (Abstract for WO 9747601, Dec. 18, 1997). 1998.
Gazi et al., British Journal of Pharmacology, vol. 124, pp. 889-896. 1998.
Nityanand et al. Chemical Abstracts, vol. 78, No. 119132, 1973.
Kulagowski et al. Current Pharmaceutical Design,3, pp. 355-366, 1997.
Reynolds,Drugs, 51(1) pp. 7-11, 1996.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Dopamine D4 receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dopamine D4 receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dopamine D4 receptor antagonists will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2426574

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.