Dopamine-.beta.-hydroxylase inhibitors

Details Dopamine-.beta.-hydroxylase inhibitors Dopamine-.beta.-hydroxylase inhibitors

1986-08-28

1988-08-02

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544366, 544400, A61K 31495, C07D40306, C07D29510

Patent

active

047614153

ABSTRACT:
Potent dopamine-.beta.-hydroxylase inhibitors having the Formula ##STR1## that are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmaceutical compositions including these inhibitors, and methods of using these inhibitors to inhibit dopamine-.beta.-hydroxylase activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented inhibitors.

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