Dopamine and noradrenergic reuptake inhibitors in treatment of s

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514327, A61K 31415, A61K 31445

Patent

active

054479487

ABSTRACT:
Mazindol and other dopamine and/or noradrenergic reuptake inhibitors are effective to treat negative symptoms in schizophrenia.

REFERENCES:
patent: 5177081 (1993-01-01), Kaminski
patent: 5190965 (1993-03-01), Ruigt et al.
Delwaide et al., "Mazindol in the Treatment of Parkinson's Disease," Arch. Neurol., vol. 40, pp. 788-790 (Dec. 1983).
Krumholz et al., "Clinical Evaluation of Mazindol in Chronic Schizophrenics," Current Therapeutic Research, vol. 12, No. 9, pp. 609-610 (Sep. 1970).
Joyce et al., Biosis, AN 89:162887, BA87:84988, 1988.
Chinaglia et al., Medline, AN 93063820, 1992.
Hirai et al., Medline, AN 89126127, 1988.

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