Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-11-19
2000-06-13
Allen, Marianne P.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
536 235, 4353201, 435325, C12N 1512
Patent
active
060748419
ABSTRACT:
The present invention relates to the identification and characterization of a novel gene called don-1 related to epidermal growth factors (EGF) such as the neuregulins, and methods of preparing and using alternate splice forms of this gene to express new Don-1 polypeptides.
REFERENCES:
patent: 5912326 (1999-06-01), Chang
Suibuya in The Protein Kinase FactsBook, Protein Tyrofine Kinases eds. Hardie & Hanks. Academic Press. pp. 165-167, 1995.
Culousco et al. J. Biol. Chem. 270, 12857-12863, 1995.
Stratagene Cloning Systems Catalog, pp. 304-305, 1994.
Ben-Baruch et al., "Neu Differentiation Factors: A Family of Alternatively Spliced Neuronal and Mesenchymal Factors" Proc. Soc. Exp. Biol. Med. 206:221-227, 1994.
Prigent et al., "The Type 1 (EGFR-Related) Family of Growth Factor Receptors and their Ligands" Prog. Growth Factor Res. 4:1-24, 1992.
Slamon et al., "Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2
eu Oncogene" Science 235:177-182, 1982.
Tzahar et al., "Erb-3 and ErbB-4 Function as the Respective Low and High Affinity Receptors of All Neu Differentiation Factor/Heregulin Isoforms" J. of Biol. Chem. 269:25226-25233, 1994.
Wen et al., "New Differentiation Factor: A Transmembrane Glycoprotein Containing on EGF Domain and an Immunoglobulin Homology Unit" Cell 69:559-572, 1992.
Nierman et al., eds., ATCC/NIH Respository Catalogue of Human and Mouse DNA Probes and Libraries, 1994, pp. 1-70; see pp. 1-58.
Copy of International Search Report dated Dec. 23, 1997.
Busfield Samantha J.
Gearing David P.
Allen Marianne P.
Millennium BioTherapeutics, Inc.
LandOfFree
Don-1 gene and polypeptides and uses therefor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Don-1 gene and polypeptides and uses therefor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Don-1 gene and polypeptides and uses therefor will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2067509