Dolastatins A and B cell growth inhibitory substances

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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Details

260112R, 424 95, A61K 3702, C07G 700

Patent

active

044864140

ABSTRACT:
Potent cell growth inhibitory substances have been obtained from the Indian Ocean sea hare Dolabella. These substances have been given the names dolastatin A and dolastatin B. These compounds are characterized by physical and chemical parameters.

REFERENCES:
patent: 4414205 (1983-11-01), Pettit
Watson-Ph.D. Dissert (Abs.) Univ. Microfilms, Inc. Ann Arbor, Mi, (1969).
Engel-Zool, Med. Leiden, vol. 24, (1945), pp. 197-239.

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