DNAs that code for mouse interleuken 4

Details DNAs that code for mouse interleuken 4 DNAs that code for mouse interleuken 4

1986-09-30

1995-05-16

Ellis, Joan

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 691, 435 6951, 4351723, 43525233, 4353201, 530300, 530350, 935 10, 935 18, 935 29, 935 41, 935 56, 935 73, C12P 2102, C12P 1934, C12N 1500, C12N 121, C07K 300, C07H 1512, A61K 3702

Patent

active

054162017

ABSTRACT:
Mouse IgG.sub.1 inducing factor and the DNA that codes for the same were isolated by using a novel genetic technique, and their structures determined by the dideoxy chain termination method. The mouse IgG.sub.1 inducing factor obtained by the method of this invention has activity to improve immune response in living bodies and are hence useful for the treatment and prevention of infectious diseases, AIDS, functional immunodeficiency and the like. This factor, or part of its amino acid sequence, may also be used for the preparation of antibody against the same. In addition, it is possible to use this factor as a model for the synthesis of other polypeptides having similar structures, and for many other purposes.

REFERENCES:
Sideras et al. Eur. J. Immunol. 1985(15) 593-598.
Lee, F. et al, Proc. Natl. Acad. Sci. USA, 83:2061-2065 (1986).
Noma, Y. et al., Nature, 319:640-646 (1986).

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