DNA vectors encoding a novel human growth hormone-variant protei

Details DNA vectors encoding a novel human growth hormone-variant protei DNA vectors encoding a novel human growth hormone-variant protei

1984-03-01

1987-06-02

Martinell, James

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 68, 435 70, 435 91, 4351723, 435241, 435243, 435253, 536 27, 935 13, 935 29, 935 31, 935 32, 935 66, C12N 500, C12N 1500, C12N 502, C12N 100, C12N 120, C12P 2100, C12P 2102, C12P 1934, C07H 2104

Patent

active

046703934

ABSTRACT:
A novel non-allelic human growth hormone variant encoding gene is isolated using recombinant DNA techniques. The human growth hormone variant gene or a human growth hormone variant gene fused to a presequence may be inserted into cloning or expression vehicles which in turn may be used to transform cells in culture.

REFERENCES:
Lewin x Gene Expression, vol. 2, Eucaryotic Chromosomes, 1974, John Wiley & Sons Ltd, London, pp. 148-153.
Ross et al, "The Human Growth Hormone Gene Family", Chem. Abstr. 98: 177038g (1983) of Horm. Drugs. Proc. FDA-USP Workshop Drug Ref. Stand. Insulins, Somatotropins, Thyroid-Axis Horm. (1982) pp. 313-318.
Pavlakis et al, "Expression of Two Human Growth Hormone Genes in Monkey Cells Infected by Simian Virus 40 Recombinants", Proc. Natl. Acad. Sci. USA 78: 7398 (1981).

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