Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1997-11-07
2000-05-16
Wortman, Donna C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4241991, 935 56, A61K 3912
Patent
active
060633859
ABSTRACT:
Disclosed herein are methods for vaccinating mammals against parvovirus. In one form, a recombinant, replication incompetent vector containing DNA coding for canine parvoviral capsid protein is administered to a dog while the pup's maternal antibodies are still functioning. This acts to prime T-helper cells. A second administration of either canine parvoviral capsid protein, or a construct capable of expressing it, is then administered. The latter administration immunizes the mammal notwithstanding the maternal antibody effect.
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Brumback Brenda G.
Wisconsin Alumni Research Foundation
Wortman Donna C.
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