Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-09-18
2000-07-18
Celsa, Bennett
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, 435 915, 436173, 935 8, 935 17, 935 77, 935 78, C07H 2104, C12P 1934, C12Q 168
Patent
active
060905581
ABSTRACT:
The present invention is related to the fields of genetic mapping and genetic identity detection, including forensic identification and paternity testing. This invention is more specifically directed to the use of mass spectrometry to detect length variation in DNA nucleotide sequence repeats (including variants of common alleles), such as microsatellites and short tandem repeats, and to DNA sequences provided as primers for the analysis of DNA tandem nucleotide repeat polymorphisms at specific loci on specific chromosomes.
REFERENCES:
patent: 4683202 (1987-07-01), Mullis
patent: 5075217 (1991-12-01), Weber
patent: 5364759 (1994-11-01), Caskey et al.
patent: 5369004 (1994-11-01), Polymeropoulos et al.
patent: 5378602 (1995-01-01), Polymeropoulos et al.
patent: 5468610 (1995-11-01), Polymeropoulos et al.
patent: 5496562 (1996-03-01), Burgoyne
patent: 5503980 (1996-04-01), Cantor
patent: 5547835 (1996-08-01), Koster
patent: 5580733 (1996-12-01), Levis et al.
patent: 5582979 (1996-12-01), Weber
patent: 5599666 (1997-02-01), Schumm et al.
patent: 5605798 (1997-02-01), Koster
patent: 5625184 (1997-04-01), Vestal et al.
patent: 5627369 (1997-05-01), Vestal et al.
patent: 5661028 (1997-08-01), Foote
patent: 5674686 (1997-10-01), Schumm et al.
patent: 5691141 (1997-11-01), Koster
patent: 5700642 (1997-12-01), Monforte et al.
patent: 5762876 (1998-06-01), Lincoln et al.
patent: 5766847 (1998-06-01), Jackle et al.
patent: 5853989 (1998-12-01), Jeffreys et al.
patent: 5885775 (1999-03-01), Haff et al.
patent: 5888819 (1999-03-01), Goelet et al.
Alford et al., "Rapid and efficient resolution of parentage by amplification of short tandem repeats," Am. J. Hum. Genet., 55: 190-195, 1994.
Anker et al., "Tetranucleotide repeat polymorphism at the human thyroid peroxidase (hTPO) locus," Hum. Mol. Genet., 1:137, 1992.
Becker et al., "Genetic analysis of short tandem repeat loci by time of flight mass spectrometry," Seventh International Symposium on Human Identification (1996), pp. 158-162, 1997.
Braun et al., "Detecting CFTR gene mutations by using primer oligo base extension and mass spectrometry," Clin. Chem. 43:1151-1158, 1997.
Braun et al., "Improved Analysis of Microsatellites Using Mass Spectrometry," Genomics 46:18-23, 1997.
Butler et al., "High-throughput STR Analysis by Time-of-Flight Mass Spectrometry," Proceedings of the Second European Symposium on Human Identification 1998, Promega Corporation, in press (1998).
Butler et al., "Rapid and Automated Analysis of Short Tandem Repeat Loci Using Time-of-Flight Mass Spectrometry," Proceedings of the Eighth International Symposium on Human Identification 1997, Promega Corporation, pp. 94-101, 1998.
Butler et al., "Reliable Genotyping of Short Tandem Repeat Loci without an Allelic Ladder Using Time-of-Flight Mass Spectrometry," Int. J. Legal Med., in press (1998).
Crain, "Nucleic acids: overview and analytical strategies," In: Mass Spectrometry in Biomolecular Sciences, Caprioli et al., Eds., Kluwer Academic Publishers, Netherlands, pp. 351-379, 1996.
Dubovsky et al., "Sets of short tandem repeat polymorphisms for efficient linkage screening of the human genome," Hum. Mol. Genet., 4:449-452, 1995.
Edwards et al., "DNA typing and genetic mapping with trimeric and tetrameric tandem repeats," Am. J. Hum. Genet., 49:746-756, 1991.
Fregeau and Fourney,"DNA typing with fluorescently tagged short tandem repeats: a sensitive and accurate approach to human identification," BioTechniques, 15:100-119, 1993.
Hammond et al., "Evaluation of 13 short tandem repeat loci for use in personal identification applications," Am. J. Hum. Genet., 55:175-189, 1994.
Hauge and Litt, "A study of the origin of `shadow bands` seen when typing dinucleotide repeat polymorphisms by the PCR.TM.," Hum. Mol. Genet., 2:411-415, 1993.
Hearne and Todd, "Tetranucleotide repeat polymorphism at the HPRT locus," Nucleic Acids Res., 19:5450, 1991.
Huang et al., "Chinese Population data on three tetrameric short tandem repeat loci-HUMTh01, TPOX, and CSF1PO--derived using mutiplex PCR and manual typing," Forensic Sci. Int. 71:131-136, 1995.
Jacobson et al., "Applications of mass spectrometry to DNA sequencing," GATA, 8(8):223-229, 1991.
Karas et al., "Matrix-assisted laser desorption ionization mass spectrometry," Mass Spectrom. Rev., 10:335-357, 1991.
Kayser et al., "Evaluation of Y-chromosomal STRs: a multicenter study," Int. J. Legal Med. 110:125-133, 1997.
Kimpton et al., "Automated DNA profiling employing multiplex amplification of short tandem repeat loci," PCR.TM. Meth. Appl., 3:13-22, 1993.
Kimpton et al., "Validation of highly discriminating multiplex short tandem repeat amplification systems for individual identification," Electrophoresis, 17:1283-1293, 1996.
Kimpton et al., "A further tetranucleotide repeat polymorphism in the vWF gene," Hum. Mol. Genet., 1:287, 1992.
Kirpekar et al., "Matrix assisted laser desorption/ionization mass spectrometry of enzymatically systhesized RNA up to 150 kDa," Nucleic Acids Research, 22(19):3866-3870, 1994.
Lareu et al., "A highly variable STR at the D12S391 locus," Int. J. Leg. Med., 109:134-138, 1996.
Lee, et al., Comparison on short tandem repeat (STR) detection using silver, fluorescence and matrix assisted laser desorption ionization time-of-flight mass spectrophotometry (MALDITOF-MS), Proceedings of the Sixth International Symposium on Human Identification, published by Promega Corp., 1995.
Limbach et al., "Characterization of oligonucleotides and nucleic acids by mass spectrometry," Curr. Opin. Biotech., 6:96-102, 1995.
Little et al., "MALDI on a Chip: Analysis of Arrays of Low-Femtomole to Subfemtomole Quantities of Synthetic Oligonucleotides and DNA Diagnostic Products Dispensed by a Piezoelectric Pipet," Anal. Chem. 69:4540-4546, 1997.
Little et al., "Mass Spectrometry from Miniaturized Arrays for Full Comparative DNA Analysis," Nature Med. 3:1413-1416, 1997.
Liu et al., "Rapid screening of genetic polymorphisms using buccal cell DNA with detection by matrix-assisted laser desorption/ionization mass spectrometry," Rapid Commun. in Mass Spectrometry, 9:735-743, 1995.
Lygo et al., "The validation of short tandem repeat (STR) loci for use in forensic casework," Int. J. Leg. Med., 107:77-89, 1994.
Nordhoff et al., "Matrix-assisted laser desorption/ionization mass spectrometry of nucleic acids with wavelengths in the ultraviolet and infrared," Rapid Commun. in Mass Spectrom., 6:771-776, 1992.
Parr, Fitzgerald and Smith, "Matrix-assisted laser desorption/ionization mass spectrometry of synthetic oligdoeoxyribonucleotides," Rapid Commun. in Mass Spectrom., 6:369-372, 1992.
Pease, et al., "Light-generated oligonucleotide arrays for rapid DNA sequence analysis," Proc. Natl. Acad. Sci. USA, 91:5022-5026, 1994.
Polymeropoulos et al., "Tetranucleotide repeat polymorphism at the human c-fes/fps proto-oncogene (FES)," Nucleic Acids Res., 19:4018, 1991.
Polymeropoulos et al., "Tetranucleotide repeat polymorphism at the human coagulation factor XIII A subunit gene (F13A1)," Nucleic Acids Res., 19:4306, 1991.
Polymeropoulos et al., "Tetranucleotide repeat polymorphism at the human tyrosine hydroxylase gene(TH)," Nucleic Acids Res., 19:3753, 1991.
Polymeropoulos et al., "Dinucleotide repeat polymorphism at the human CTLA4 gene," Nucleic Acids Res., 19:4018, 1991.
Polymeropoulos et al., "Trinucleotide repeat polymorphism at the human met-tRNA-i gene 1 (TRMI)," Nucleic Acids Res., 19:4306, 1991.
Polymeropoulos et al., "Dinucleotide repeat polymorphism at the human non-histone chromosomal protein HMG14 gene," Nucleic Acids Res., 19:3753, 1991.
Puers et al., "Allele ladder characterization of the short tandem repeat polymorphism located in the 5' flanking region to the human coagulation factor XIII A subunit gene," Genomics, 23:260-264, 1994.
Puers et al., "Identification of repeat sequence heterogeneity at the polymorphic short tandem repeat locus HUMTH01[AATG]n and reassignment of alleles in population analysis by using a locus-specific allele ladder," Am. J. Hum. Genet., 53:953-958, 1993.
Roewer et al., "Simple repeat sequences on the human Y chromo
Becker Christopher H.
Butler John M.
Li Jia
Monforte Joseph A.
Celsa Bennett
Genetrace Systems, Inc.
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