DNA Transfer vector and transformed microorganism containing hum

Details DNA Transfer vector and transformed microorganism containing hum DNA Transfer vector and transformed microorganism containing hum

1982-06-08

1984-02-14

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 68, 435172, 435317, C12N 120, C12N 1500, C12N 100, C12P 2100

Patent

active

044317409

ABSTRACT:
A DNA having a base sequence coding for human proinsulin and a DNA having a base sequence coding for human pre-proinsulin have been cloned, and novel recombinant DNA transfer vectors containing said cloned DNAs have been constructed. Novel microorganisms transformed by said recombinant transfer vectors have been obtained. Certain of said transformed microorganisms have demonstrated capability to express the cloned DNA's, synthesizing a protein comprising human proinsulin and a protein-comprising human pre-proinsulin.

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