Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1989-04-20
1991-08-27
Teskin, Robin L.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
4323201, 432 91, 432255, 432256, 432232, 4321723, 536 27, 426 11, 426 12, 935 56, 935 69, C12P 2100, C12C 100, C12G 100, C07H 1512
Patent
active
050432761
ABSTRACT:
DNA strand having an ability in biotechnological production of .alpha.-acetolactate decarboxylase is disclosed. The DNA strand is characterized in that it has a nucleotide sequence coding for a polypeptide whose amino acid sequence is substantially from A to B of FIG. 1 and which has .alpha.-acetolactate decarboxcylase activity. Also disclosed is a yeast which belongs a Saccharomyces cerevisiae and which has been transformed by the DNA strand. The yeast is characterized by the fact that its .alpha.-acetolactate producing ability is reduced, and will thus produce an alcoholic liquor such as beer which contains no or little diacetyls which have come from their precursor, namely .alpha.-acetolactate.
REFERENCES:
patent: 4617273 (1926-10-01), Olsen
patent: 4895802 (1980-01-01), Sone et al.
"Cloning and Expression-" Goelling et al.; Applied and Environmental Microbiology 1889-1891 (1988).
"Molecular Cloning-" H. Sone; Journal of Biotechnology vol. 5, 1987.
Article "Acetolactate Decarboxylase from Aerobacter . . . " Loken et al.; Eur. J. Biochem. 14, 1970, 133-137; Article 2,3-Butanediol Biosynthetic-Stromer; Methods in Enzymology, vol. 41, pp. 518-533.
Article "Use of A-Acetolactate-" Godtfredsen et al. Proceedings of the European Brewery Convention, 1986 pp. 161-168
Carlsberg Res. Commun., vol. 48, 1983, pp. 239-247; S. E. Godtfredsen: "On the Occurrence of Alpha-Acetolactate Decarboxylases Among Microorganisms".
EBC Congress 1983, vol. 89, lecture No. 17, pp. 161-168; S. E. Godtfredsen et al.: "Use of Alpha-Acetolactate Decarboxylase for Accelerated Maturation of Beer".
Inoue Takashi
Tanaka Junichi
Yamano Shigeyuki
Kirin Beer Kabushiki Kaisha
Teskin Robin L.
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