Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2011-05-10
2011-05-10
Benzion, Gary (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
Reexamination Certificate
active
07939264
ABSTRACT:
The present invention pertains to a method for determining the sequence of a polynucleotide, the method relying on the detection of a conformational change in an enzyme that interacts with and processes along the polynucleotide. The detection of a conformational change may be carried out by measuring changes in a fluorophore bound to the enzyme.
REFERENCES:
patent: 5360714 (1994-11-01), Seeger
patent: 5620854 (1997-04-01), Holzrichter et al.
patent: 5747247 (1998-05-01), Kowalczykowski et al.
patent: 5753439 (1998-05-01), Smith et al.
patent: 5801042 (1998-09-01), Chang et al.
patent: 6159687 (2000-12-01), Vind
patent: 6210896 (2001-04-01), Chan
patent: 6221642 (2001-04-01), O'Donnell
patent: 6263286 (2001-07-01), Gilmanshin et al.
patent: 6331392 (2001-12-01), Laing et al.
patent: 6335420 (2002-01-01), Bruening et al.
patent: 6355420 (2002-03-01), Chan
patent: 6908736 (2005-06-01), Densham
patent: 7008766 (2006-03-01), Densham
patent: 7604963 (2009-10-01), Densham
patent: 7608397 (2009-10-01), Densham
patent: 2003/0044781 (2003-03-01), Korlach et al.
patent: 2004/0241678 (2004-12-01), Densham
patent: 2004/0241719 (2004-12-01), Densham
patent: 2005/0214849 (2005-09-01), Densham
patent: 2008/0014592 (2008-01-01), Densham
patent: 2009/0029383 (2009-01-01), Densham
patent: WO 90/05303 (1990-05-01), None
patent: WO 90/13666 (1990-11-01), None
patent: WO 91/06678 (1991-05-01), None
patent: WO 93/21340 (1993-10-01), None
patent: WO 94/21822 (1994-09-01), None
patent: WO 95/06138 (1995-03-01), None
patent: WO 99/05315 (1999-02-01), None
patent: WO 00/09757 (2000-02-01), None
patent: WO 00/53805 (2000-09-01), None
patent: WO 00/60114 (2000-10-01), None
Furey, S. et al. “Use of Fluorescence Resonance Energy Transfer to Investigate the Conformation of DNA Substrates Bound to the Klenow Fragment”Biochemistry, 1998, pp. 2979-2990, vol. 37, XP-002171248.
Ha, T. et al. “Probing the interaction between two single molecules: Fluorescence resonance energy transfer between a single donor and a single acceptor”Proc. Natl. Acad. Sci. USA, 1996, pp. 6264-6268, vol. 93, XP-002171249.
Ha, T. et al. “Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism”Proc. Natl. Acad. Sci. USA, 1999, pp. 893-898, vol. 96, XP-002171247.
Weiss, S. “Fluorescence Spectroscopy of Single Biomolecules”Science, 1999, pp. 1676-1683, vol. 283, XP-002171250.
Schwarz, T., et al., “Detection of nucleic acid hybridization using surface plasmon resonance”Tibtech, 1991, pp. 333-340, vol. 9, Elsevier Science Publishers Ltd., U.K.
Sutton, M., et al., “Ercherichia coliDnaA Protein”,J. Biol. Chem., 1998, pp. 34255-34262, vol. 273, No. 51, The American Society for Biochemistry and Molecular Biology, Inc., U.S.A.
Benzion Gary
Devernoe David L.
Gen-Probe Incorporated
Wilder Cynthia B
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