DNA sequencing by extension of probe chip immobilized oligonucle

Details DNA sequencing by extension of probe chip immobilized oligonucle DNA sequencing by extension of probe chip immobilized oligonucle

1995-06-05

1998-04-21

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 536221, 536 231, 536 2431, 536 243, C12Q 168, C12P 1934, C07H 2104

Patent

active

057416443

ABSTRACT:
The method of base sequence determination according to the present invention ensures an effective determination of a long DNA base sequence, by providing simultaneous determination of base sequences of two or more positions of the long DNA or base sequences of two or more DNAs, using the DNA probe chip which classifies and retains the DNA oligomers having various sequences, and using fluorophorelabeled primers which have the same sequencies as the oligomers in the chip and are labeled by various fluorophores, then followed by the extension of the determined base length by re-selection of the primers complementary to the sequence thus determined.

REFERENCES:
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5202231 (1993-04-01), Drmanac et al.
patent: 5412087 (1995-05-01), McGall et al.
patent: 5429807 (1995-07-01), Matson et al.
patent: 5434049 (1995-07-01), Okano et al.
patent: 5492806 (1996-02-01), Drmanac et al.
patent: 5510270 (1996-04-01), Fodor et al.
patent: 5525464 (1996-06-01), Drmanac et al.
patent: 5547839 (1996-08-01), Dower et al.
patent: 5552270 (1996-09-01), Khrapko et al.
Drmanac et al, "Reliable hybridization of oligonucleotides as short as six nucleotides", DNA Cell Biol. 9(7):527-534, 1990.
Southern et al, "Analyzing and comparing nucleic acid sequences by hybridization to arrays of oligonucleotides: Evaluation using experimental models", Genomics 13:1008-1017, Aug. 1992.
Habener et al, Proceedings of the National Academy of Sciences, USA, vol. 85, pp. 1,735-1,739 (Mar. 1988).
Seela et al, Nucleic Acids Research, vol. 14, pp. 1,825-1,844 (1986).
Morrison et al, Analytical Biochemistry, vol. 183, pp. 231-244 (Jun. 1989).
Rasmussen et al, Analytical Biochemtistry, vol. 198, pp. 138-142(Apr. 1991);.
Prober et al, Science, vol. 238, pp. 336-341 (Oct. 1987).
Strezoska et al, Proc. Nat. Acad. Sci., USA, vol. 88, pp. 10089-10093, (Nov., 1991).
Smith et al, Nature, vol. 321, pp. 674-679, (Jun. 1986).
U.S. Patent Application Ser. No. 08/021,667, Polynucleotide Capturing Tip and Polynucleotide Preparative Method and Detection Method Using Same.
Baringa, M., "Will DNA Chip Speed Genome Initiative", (1991) Science, 253:1489.
Rasmussen et al. "Covalent Immobilization of DNA onto Polystyrene Microwells", (1991) Analytical Biochemistry, 198:138-142.
Khrapko et al., "A Method for DNA Sequencing by Hybridization with Oligonucleotide Matrix", DNA Sequence (1991) vol 1: 375-388.
Brumbaugh et al. "Continuous, On-Line DNA Sequencing Using Digodeoxynucleotide Primers with Multiple Fluorophores" (1988) P.N.A.S. 85: 5610-5614.
Maniatis et al. "Molecular Cloning A Laboratory Manual" Cold Spring Harbor Lab., N.Y. 1989. pp. 5,3-58, 13.6.
Nelson et al, PNAS 86(1989) pp. 6686-6690.

Affiliated with

Also associated with

Rating

DNA sequencing by extension of probe chip immobilized oligonucle does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA sequencing by extension of probe chip immobilized oligonucle, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA sequencing by extension of probe chip immobilized oligonucle will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2056642