DNA sequences of enterically transmitted non-A/non-B hepatitis v

Details DNA sequences of enterically transmitted non-A/non-B hepatitis v DNA sequences of enterically transmitted non-A/non-B hepatitis v

1994-07-25

1998-08-04

Sisson, Bradley L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2432, 435 5, 435 6, 43525233, 4353201, 436 94, 935 1, 935 8, 935 66, 935 73, C07H 2104, C12Q 170, G01N 3320, C12N 1500

Patent

active

057895597

ABSTRACT:
Nucleic acid sequences derived from enterically transmitted nonA
onB viral hepatitis agent (HEV) are disclosed. DNA sequences encoding specific epitopes within viral protein sequences that are reactive with sera of individuals infected with different strains of HEV are also disclosed. These DNA sequences and fragments thereof are useful for identifying and sequencing the entire viral agent and for assaying the presence of the viral agent in an infected sample, for example by using specific amplification of virus-derived DNA sequences, as well as for producing viral proteins or polypeptides.

REFERENCES:
patent: 4659678 (1987-04-01), Forrest et al.
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4871659 (1989-10-01), Pillot
patent: 5077193 (1991-12-01), Mishiro et al.
New Enbland Bio Labs 1988-1989 Catalog, p. 62.
Lewin, R., "When Does Homology Mean Something Else?", Science, vol. 237, Sep. 1987, p. 1570.
Sarthou, et al., "Characterization of an antigen-antibody system associated associated with epidimic non-A, non-B hepatitis in West Africa . . . " Ann. Inst. Pasteur/Virl., 137: 225-232 (1986).
Sigma Chemical Company, "Sigma Price List 1987", p. 1024, (1987).
Computer generated sequence comparison--source: GenBank.

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