Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Patent
1994-12-28
1998-06-16
Hutzell, Paula K.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
4353201, 4352523, 536 235, 935 9, C12N 1513, C12N 510, C12N 1563, C12N 121
Patent
active
057669430
ABSTRACT:
This invention discloses the isolation and purification of gene sequences which code upon expression a soluble form of the traditionally membrane bound immuno-regulatory protein, CD23. This protein regulates the amount of IgE present in the blood and upon cloning and amplification, procedures may be used in the treatment of IgE mediated diseases.
REFERENCES:
Kikutani et al. Cell 47 (1986) 657-665.
Ikuta et al. PNAS 84 (1987) 819-823.
Ludin et al. EMBO J. 6(1987) 109-114.
Uchibayashi et al. J. Immunol. 142(1989) 3901-3908.
Gollnick et al. J. Immunol. 144(1990) 1974-1982.
Bettler et al. PNAS 86 (1989) 7566-7570.
Lynch Richard G.
Matsui Minoru
Nunez Rafael M.
Yodoi Junji
Hayes Robert C.
Hutzell Paula K.
University of Iowa Research Foundation
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