DNA sequences expressing mammalian .alpha..sub.1 -antitrypsin

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 691, C12P 2102

Patent

active

060251611

ABSTRACT:
DNA sequences to mammalian .alpha..sub.1 -antitrypsin are provided which can be used for expression of mammalian .alpha..sub.1 -antitrypsin.
This work was supported in part by grants HL16919 and HL27509 from the National Institutes of Health.

REFERENCES:
patent: 4530901 (1985-07-01), Weissman
patent: 5399684 (1995-03-01), Davie et al.
patent: 5736379 (1998-04-01), Davie et al.
Wallace et al., "Hybridization of synthetic oligodeoxyribonucleotides to .phi..sub.x 174 DNA: the effect of base pair mismatch," Nucleic Acids Res. 6:3543-3557, 1979.
Suggs et al., "Use of synthetic oligonucleotides as hybridization probes: Isolation of cloned cDNA sequences for human .beta..sub.s -microglobulin," Proc. Natl. Acad. Sci. USA 78:6617, 1981.
Wilson et al., "Isolation of human alpha-1 anti trypsin mRNA from liver tissue for molecular cloning" in J. Supramol. Struct. Cell. Biochem. (Suppl. 5) 1981, 421, Abstract No. 1133, presented at the ICN-University of California at Los Angeles, Mar. 15-20, 1981.
Kurachi et al., "Cloning and sequence of cDNA coding for a lpha-1-antitrypsin", Proc. Nat. Acad. Sci. USA 78:6826, 1982/1981.
Clissold et al., "Molecular Cloning of cDNA sequences transcribed from mouse liver endoplasmic reticulum poly (A)mRNA", Biol. Abstr. 73:60806 (1982. of Gene 15:225-235, 1981.
Houghton et al., "The amino-terminal sequence of human fibroblast interferon as deduced from reverse transcripts obtained using synthetic oligonucleotide primer", Nucl. Acids. Res. 8:1913, 1980.
Morii et al., "Human alph-1-antitrypsin, Characterization and N- and C- terminal sequences", J. Biochem. 83:269, 1978.
Roberts et al., "A general method for maximizing the expression of a cloned gene", Proc. Natl. Acad. Sci. USA 76:760, 1979.
Goeddel et al., "Synthesis of human fibroblast interferon by E. coli," Nucleic Acids Res. 8:4057, 1980.
Woo et al., "The human alpha-1-antitrypsin gene: its sequence homology and structural comparison with the chicken ovalbumin gene", Chem. Abstr. 98:120615Z, 1983, of UCLA Symp., Mol. Cell Biol. 26(Gene Regul.):55-64, 1982.
Shochat et al., "Primary Structure of Human .alpha..sub.1 -Protease Inhibitor," J. Biol. Chem. 253:5630-5634, 1978.
Carrell et al., "Carboxy terminal fragment of Human .alpha.-1-antitrypsin from hydroxylamine cleavage: homology with antithrombin III," Biochem. Biophys. Res. Commun. 91:1032-1037, 1979.
Mega et al., "Studies on the Oligosaccharide Chains of Human .alpha..sub.1 -Protease Inhibitor," P.J. Biol. Chem. 255:4057-4061, 1980.
Crawford, "Purification and Properties of Normal Human .alpha..sub.1 -Antitrypsin," Arch. Biochem. Biophys. 156:215-222, 1973.
Chandra et al., Biochem. Biophys. Res. Commun. 103:751-758, 1981.
Woo et al., "Induction and cloning of the .alpha..sub.1-antitrypsin gene," Federation Proceedings 40(6):1754, Abstract No. 1240, May 1, 1981.
Davie, E.W., "Cloning of fibrinogen, prothrombin, and .alpha..sub.1 -antitrypsin," The Harvey Lectures, Series 77, Academic Press, New York, pp. 1-21, 1983.
Kurachi et al., "Isolation and characterization of a cDNA clone coding for .alpha..sub.1 -antitrypsin," Abstract No. 0255, Eighth International Conference on Thrombosis and Haemostatis, Jul. 14, 1981.
Woo et al., "The human alpha-1-antitrypsin gene and pulmonary emphysema," Abstract No. 7061, Twenty-first Annual Meeting of the American Society for Cell Biology, Nov. 9-13, 1981.
Davie et al., "The structure and cloning of the .alpha..sub.1 antitrypsin gene," Protein, Nucleic Acid and Enzyme 27(12):1805-1809, 1982, based on a lecture in Nov. 1981.
Kurachi et al., "Cloning and nucleotide sequences of cDNA and genomic DNA coding for .alpha..sub.1 -antitrypsin," Fed. Proc. 41:517, Abstract No. 1446, Apr. 15-23, 1982.
Colten, H.R., et al., "Genetics and biosynthesis of complement proteins," New Engl. J. of Med. 304:653-456, 1981.
Colten, H.R., et al., "Synthesis and secretion of complement proteins by macrophages," Annals New York Academy of Sciences 332:482-490, 1979.
Reid, K.B.M., et al., "The proteolytic activation systems of complement," Ann. Rev. Biochem, 50:433-464, 1981.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

DNA sequences expressing mammalian .alpha..sub.1 -antitrypsin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA sequences expressing mammalian .alpha..sub.1 -antitrypsin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA sequences expressing mammalian .alpha..sub.1 -antitrypsin will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1904886

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.