DNA sequences encoding vascular cell adhesion molecules (VCAMS)

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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530380, 435 696, 4353201, C07K 1300, C12N 1500, C12P 2106

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052722635

ABSTRACT:
DNA sequences encoding vascular cell adhesion molecules 1 and 1b ("VCAM1" and "VCAM1B"), recombinant DNA molecules comprising those sequences, and unicellular hosts transformed with those recombinant DNA molecules.

REFERENCES:
patent: 5011778 (1991-04-01), Newman et al.
Osborn et al. 1989 Cell. 59:1203-1211.
Warrick et al. 1986. Conserved protein domains in myosin heavy chain gene from Dictyostelium discoideum PNAS 83:9433-9437.
Dixon et al. 1986. Evidence for Replicative Recombination in Cauliflower mosaic virus. Virology 150:463-468.
Mohomed et al 1988 Primary structure of the multifunctional .alpha.subunit protein of yeast fatty acid symthoesis der. 7AS2 Gene. Seq. J. Biol. Chem 263:12315.
Chen et al. 1988. Molecular cloning and Characterization of two rate Renal Kallikrein Genes Biochem. 27:7189.
Lundwall et al. 1985. Isolation and Seq. Analysis of a cDNA clone encoding the fifth complement component. J. Biol. Chem. 260:2108-2112.
Arfors, K. -E., et al., "A Monoclonal Antibody to the Membrane Glycoprotein Complex CD18 Inhibits Polymorphonuclear Leukocyte Accumulation and Plasma Leakage In Vivo", Blood, 69, pp. 338-340 (1987).
Aruffo, A., and B. Seed, "Molecular Cloning of a CD28 cDNA by a High Efficiency COS Cell Expression System", Proc. Natl. Acad. Sci. USA, 84, pp. 8573-8577 (1987).
Becker, D., et al., "Proliferation of Human Malignant Melanomas Is Inhibited by Antisense Oligodeoxynucleotides Targeted Against Basic Fibroblast Growth Factor", EMBO J., 8, pp. 3685-3691 (1989).
Benchimol., S., et al., "Carcinoembryonic Antigen, a Human Tumor Marker, Functions as an Intercellular Adhesion Molecule", Cell, 57, pp. 327-334 (1989).
Bevilacqua, M. P., and M. A. Gimbrone, "Inducible Endothelial Functions in Inflammation and Coagulation", Seminars in Thrombosis and Hemostasis, 13, pp. 425-433 (1987).
Bevilacqua, M. P., et al., "Interleukin I Acts on Cultured Human Vascular Endothelium to Increase the Adhesion of Polymorphonuclear Leukocyctes, Monocytes, and Related Leukocyte Cell Lines", J. Clin. Invest., 76, pp. 2003--2011 (1985) ("Bevilacqua I").
Bevilacqua, M. P., et al., "Endothelial-Dependent Mechanisms of Leukocyte Adhesion: Regulation by Interleukin-1 and Tumor Necrosis Factor", in Leukocyte Emigration and Its Sequelae (S. Karger A. G. Switzerland 1987), pp. 79-93 ("Bevilacqua II").
Bevilacqua, M. P., et al., "Identification of an Inducible Endothelial-Leukocyte Adhesion Molecule", Proc. Natl. Acad. Sci. USA, 84, pp. 9238-9242 (1987) ("Bevilacqua III").
Bevilacqua, M. P., et al., "Endothelial Leukocyte Adhesion Molecule 1: An Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins", Science, 243, pp. 1160-1165 (1989) ("Bevilacqua IV").
Brenan, M. and C. R. Parish, "Intracellular Fluorescent Labelling of Cells for Analysis of Lymphocyte Migration", J. Immun. Meth., 74, pp. 31-38 (1984).
Capon, D. J., et al., "Designing CD4 Immunoadhesins for AIDS Therapy", Nature, 337, pp. 525-531 (1989).
Carlsson, R., and C. Glad, "Monoclonal Antibodies into the '90s", Bio/Technology, 7, pp. 567-573 (Jun. 1989).
Cate, R., et al., "Isolation of the Bovine and Human Genes for Mullerian Inhibiting Substance and Expression of the Human Gene in Animal Cells", Cell, 45, pp. 685-698 (1986).
Cech, T. R., "Ribozymes and Their Medical Implications", J. Amer. Med. Assn., 260, pp. 3030-3034 (1988).
Chang, S., et al., "Recombination Following Transformation of Escherichia coli by Heteroduplex Plasmid DNA Molecules", Gene, 29, pp. 255-61 (1984).
Cotran, R. S., et al., "Induction and Detection of a Human Endothelial Activation Antigen In vivo", J. Exp. Med., 164, pp. 661-666 (1986).
Cotran, R. S., and J. S. Pober, "Endothelial Activation: Its Role in Inflammatory and Immune Reactions", in Endothelial Cell Biology, Simionescu and Simionescu, Eds., (Plenum Press, New York 1988), pp. 335-347.
Dana, N., et al., "Mol Surface Glycoprotein: Structure, Function and Clinical Importance", Pathol. Immunopathol. Res., 5, pp. 371-383 (1986).
Davis, M. M., "Subtractive cDNA Hybridization and the T-Cell Receptor Genes", Handbook of Experimental Immunology In Four Volumes, 4th ed. Blackwell Scientific Publications, Oxford, England (1986), pp. 76.1-76.13.
Davis, M. M., et al., "Cell Type-Specific cDNA Probes and the Murine I Region: The Localization and Orientation of A.sup.d ", Proc. Natl. Acad. Sci. USA, 81, pp. 2194-2198 (1984).
Devereux, J., et al., "A Comprehensive Set of Sequence Analysis Programs for the VAX", Nucl. Acids. Res., 12, pp. 387-395 (1984).
Duguid, J. R., et al., "Isolation of cDNAs of Scrapie-Modulated RNAs by Subtractive Hybridization of a cDNA Library", Proc. Natl. Acad. Sci. USA, 85, pp. 5738-5742 (1988).
Dustin, M. L., and T. A. Springer, "Lymphocyte Function-Associated Antigen-1 (LFA-1) Interaction with Intercellular Adhesion Molecule 1 (ICAM1) One of at Least Three Mechanisms for Lymphocyte Adhesion to Cultured Endothelial Cells", J. Cell. Biol., 107, pp. 321-331 (1988).
Dustin, M. L., et al., "Induction by ILI and Interferongamma: Tissue Distribution, Biochemistry, and Function of a Natural Adherence Molecule (ICAM-1)", J. Immunol., 137, pp. 245-254 (1986).
Ellison, J. W., et al., "The Sequence of a Human Immunoglobulin C-gamma-1 Gene", Nucl. Acids Res., 10, pp. 4071-4079 (1982).
Feinberg, A. P., and B. Vogelstein, "A Technique for Radiolabeling DNA Restriction Endonuclease Fragments to High Specific Activity", Anal. Biochem., 132, pp. 6-13 (1983).
Feinberg, A. P. and B. Vogelstein, "A Technique for Radiolabeling DNA Restriction Endonuclease Fragments to High Specific Activity", Anal. Biochem., 137, pp. 266-267 (1984) (Addendum).
Fisher, R. A., et al., "HIV Infection is Blocked In Vitro by Recombinant Soluble CD4", Nature, 331, pp. 76-78 (1988).
Gimbrone, M. A., "Culture of Vascular Endothelium", Prog. Hemostasis Thromb., 3, pp. 1-28 (1976).
Gimbrone, M. A., "Blood Vessels and the New Mediators of Inflammation", Lab. Invest., 46, pp. 454-455 (1982).
Goding, W., ed., Monoclonal Antibodies: Principles and Practice, Chapter 3, (Academic Press, New York, 1983).
Goldenberg, D. M., "Targeted Cancer Treatment," Immunology Today, 10, pp. 286-288 (1989).
Gubler, U., and Hoffman, B. J., "A Simple and Very Efficient Method for Generating cDNA Libraries", Gene, 25, pp. 263-269 (1983).
Hambor, J. E., et al., "Functional Consequences of Anti-Sense RNA-Mediated Inhibition of CD8 Surface Expression in a Human T Cell Clone", J. Exp. Med., 168, pp. 1237-1245 (1988).
Harlan, J. M., "Leukocyte-Endothelial Interactions", Blood, 65, pp. 513-525 (1985) ("Harlan I").
Harlan, J. M., "Neutrophil-Mediated Vascular Injury", Acta Med. Scand., Suppl., 715, pp. 123-129 (1987) (Harlan II).
Harlan, J. M., et al., "The Role of Neutrophil Membrane Proteins in Neutrophil Emigration", in Leukocyte Emigration and Its Sequelae, H. Movat, ed. (S. Karger AG, Basel, Switzerland, 1987), pp. 94-104.
Haselhoff, J., and W. L. Gerlach, "Simple RNA Enzymes with New and Highly Specific Endoribonuclease Activities", Nature, 334, pp. 585-591 (1988).
Hedrick, S. M., et al., "Isolation of cDNA Clones Encoding T Cell-Specific Membrane-Associated Proteins", Nature, 308, pp. 149-153 (1984).
Hemler, M. E., "Adhesion Protein Receptors on Hematopoietic Cells", Immunol. Today, 9, pp. 109-113 (1988).
Hemler, M. E., et al., "The VLA Protein Family (Characterization of Five Distinct Cell Surface Heterodimers Each with a Common 130, 000 Molecular Weight Subunit)", J. Biol. Chem., 262, pp. 3300-3309 (1987) (Hemlar et al. I).
Hemler, M. E., et al., "Characterization of the Cell Surface Heterodimer VLA-4 and Related Peptides", J. Biol. Chem., 262, pp. 11478-11485 (1987) (Hemler et al. II).
Hirt, B., "Selective Extraction of Polyoma DNA from Infected Mouse Cell Cultures", J. Mol. Biol., 26, pp. 365-369 (1967).
Hough A., and L. Sokoloff, "Pathology", Chap. 4, Rheumatoid ArthritisP. D. Ustinger, N. J. Zugifler and G. E. Ehrlich, eds., (Lippencott, Philadelphia, 1985), pp. 49-69.
Hunkapiller, T., and L. Hood, "Diversity of the Immunoglobulin Gene Superfamily", Adv. Immunol., 44, pp. 1-63 (1989).
Huse, W. D., et al., "Generation of

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