DNA sequences encoding hybrid lymphoblastoid-leukocyte human int

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 68, 435811, 435320, 4351723, 424 85, 530351, C07H 2104, C12N 1500

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047344911

ABSTRACT:
DNA sequences encoding for novel human lymphoblastoid-leukocyte hybrid interferons. Methods of making nucleotide sequences comprising ribosome binding sites, promoter regions, and segments of human lymphoblastoid and leukocyte interferons are described. DNA sequences for hybrid interferons are cloned and expressed in plasmid vectors. Transformed microorganisms and novel lymphoblastoid-leukocyte polypeptide interferons having biological or immunological acitivity are disclosed.

REFERENCES:
patent: 4414150 (1983-11-01), Goeddel
patent: 4569908 (1986-02-01), Mark et al.

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