DNA sequences and amino acid sequences of class B beta lactamase

Details DNA sequences and amino acid sequences of class B beta lactamase DNA sequences and amino acid sequences of class B beta lactamase

1995-05-03

1996-11-05

Jones, W. Gary

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 4352402, 4352523, 43525233, 4353201, 435 713, 536 232, 536 237, C07H 2104, C12N 121, C12N 510, C12P 2100

Patent

active

055716938

ABSTRACT:
This invention is directed to the elucidation of DNA sequences encoding Class B beta-lactamase enzymes from Bacteroides fragilis and the amino acid sequences of those enzymes. This invention is also directed to screening methods for identifying antibiotics which are resistant to such beta-lactamase enzymes or for identifying compounds which inactivate such beta-lactamase enzymes.

REFERENCES:
Cuchural, G. J., et al., Antimicrob. Agents & Chemotherapy, 30, 645-648 (1986).
Esser, K., et al., Process Biochem., 5, 146-148 (1987).
Hussain, M., et al., J. Bacteriol., 164, 223-229 (1985).
Morita, K., Kyorin Igakkai Zasshi, 19, 375-387 (1988), in Chem. Abs., 110, 72332x (1989).
Nord, C. E., et al., Rev. Infect. Diseases, 12, Supp. 2, S231-234 (1990).
Thompson, J. S., J. Bacteriol., 172, 2584-2593 (1990).
Kinh et al. "A Dictionary of Gemetry", Fourth Edition, Oxford University Press, 1990, p. 125.
Valentine et al. J. Bact 170(3) 1319 (1988).
Lier et al. Nucl. Acid Res. 15(22) 9461 (1987).
Sato et al. Antimicrob Agent. Chem. 27(4) 612 (1985).

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