DNA Sequences and amino acid sequences of class B beta-lactamase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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435 691, 4351723, 4352403, 4352523, 43525233, 4353201, 435 713, 536 232, 536 237, C12N 986, C12N 120, C12N 1500, C12P 2106

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057926425

ABSTRACT:
This invention is directed to the elucidation of DNA sequences encoding Class B beta-lactamase enzymes from Bacteroides fragilis and the amino acid sequences of those enzymes. This invention is also directed to screening methods for identifying antibiotics which are resistant to such beta-lactamase enzymes or for identifying compounds which inactivate such beta-lactamase enzymes.

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