DNA sequence participating in the regulation of the expression o

Details DNA sequence participating in the regulation of the expression o DNA sequence participating in the regulation of the expression o

1992-08-21

1994-01-18

Hill, Jr., Robert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 694, 4351723, 43525233, 4353201, 536 235, 536 2351, C12N 1500, C12N 1518, C12N 121

Patent

active

052799476

ABSTRACT:
DNA sequence participating in the regulation of the expression of a DNA sequence coding for a precursor of a polypeptide.
Expression vectors containing such a sequence.
Process for the periplasmic production of a polypeptide in a strain of Gram-negative bacteria transformed by one of these vectors.
Application to the production of human growth hormone.

REFERENCES:
patent: 4945047 (1990-07-01), Legoux et al.
Pharmacia Molecular Biologicals Catalog, May 1986, pp. 96-99, Uppsala, Sweden ("Chemicals and equipment for molecular biology," pp. 96 and 99)
Shinozaki, K. et al., Gene, 24: 147-155, 1983.
Brosius, et al.; Gene Organization and Primary Structure of a Ribosomal RNA Operon from Escherichia coli; J. Mol. Biol. (1981); 148: 107-127.

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