DNA sequence of human RP-105

Details DNA sequence of human RP-105 DNA sequence of human RP-105

1996-10-16

1998-07-14

Hutzell, Paula K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 4351773, 4352523, 4353201, C07H 2104, C12N 1563

Patent

active

057806098

ABSTRACT:
Nucleic acid molecules encoding a human B cell surface molecule are provided. Polypeptides and antibodies which bind to these polypeptides are also provided. In addition, methods of detecting mutated forms of the molecule are provided.

REFERENCES:
patent: 5155218 (1992-10-01), Weinshank et al.
patent: 5348864 (1994-09-01), Barbacid
Obernolte, R. et al., "The cDNA of a human lymphocyte cyclic-AMP phosphodiesterase (PDE IV) reveals a multigene family", Gene, 1993, 129:239-247.
Wood, Jr., W.J. et al., "Isolation and Chromosomal Mapping of the Human Immunoglobulin-Associated B29 Gene (IGB)", Genomics, 1993, 16:187-192.
Miyake, et al., "RP105, A Novel B Cell Surface Molecule Implicated in B Cell Activation, Is a Member of the Leucine-Rich Repeat Protein Family", J. Immunol., 1995, 154:3333-3334.
Miyake, K., et al., "Murine B Cell Proliferation and Protection from Apoptosis with an Antibody Against a 105kD Molecule: Unresponsiveness of X-linked Immunodeficient B Cells", J. Exp. Med., 1994, 180:1217-1224.

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