DNA sequence for the human dopamine receptor D.sub.4 and express

Details DNA sequence for the human dopamine receptor D.sub.4 and express DNA sequence for the human dopamine receptor D.sub.4 and express

1990-12-07

1995-06-06

Parr, Margaret

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4353201, 435 6, 536 235, 935 22, 935 34, 935 1, C12N 120, C12N 1500, C07H 1700, C12Q 168

Patent

active

054222656

ABSTRACT:
The present invention is directed toward the human D.sub.4 dopamine receptor. The nucleotide sequence of the gene corresponding to this receptor is provided by the invention. The invention also includes a recombinant eukaryotic expression vector capable of expressing the human D.sub.4 dopamine receptor in cultures of transformed eukaryotic cells and such cultures of transformed eukaryotic cells which synthesize the human D.sub.4 dopamine receptor.

REFERENCES:
Cooper et al., The Biochemical Basis of Neuropharmacology, 3d ed. 1978 (Oxford University Press; N.Y.), pp. 161-195.
Kebabian and Calne, Nature 277; 93-96 (1979).
Senogles et al., Biochemistry 25: 749-753 (1986).
Sengoles et al., J. Biol. Chem. 263: 18996-19002 (1988).
Gingrich et al., J. Biochemistry 27: 3907-3912 (1988).
Amlaiky et al., Mol. Pharmacol. 31: 129-134 (1987).
Ninik et al., Biochemistry 27: 7594-7599 (1988).
Amlaiky and Caron, J. Biol. Chem. 260: 1983-1986 (1985).
Amlaiky and Caron, J. Neurochem. 47: 196-204 (1986).
Jarvie et al., Mol. Pharmacol. 34: 91-97 (1988).
Sokoloff et al., Nature 347: 146-151 (1990).
Seeman et al., Neuropyschopharm. 1: 5-15 (1987).
Seeman, Synapse 1: 133-152 (1987).
Bunzow et al., Nature 336: 783-787 (1988).
Grandy et al., Proc. Natl. Acad. Sci. U.S.A. 86: 9762-9766 (1989).
Dal Toso et al., EMBO J. 8: 4025-4034 (1989).
Zhou et al., Nature 347: 76-80 (1990).
Sunahara et al., Nature 347: 80-83 (1990).
Kane et al., Arch. Gen. Psychiat. 45: 789-796 (1988).
Casey, Psychopharmacology 99: S47-S53 (1989).
Ackenheil et al., Arzneim-Forsch 26: 1156-1158 (1976).
Sandoz Canada, Inc., Clozaril: Summary of preclinical and clincal data (1990).
Dohlman et al., Biochemistry 26: 2657-2664 (1987).
Davis et al. "Efficient Isolation of Genes by Using Antibody Probes", P.N.A.S., U.S.A., vol. 80, pp. 1194-1198, Mar. 1983.
Sanger et al., "DNA Sequencing with Chain-Terminating Inhibitors", P.N.A.S., U.S.A., vol. 74, No. 12, pp. 5463-5467, Dec. 1977.
Sommer, et al., Nucleic Acids Research, vol. 17, No. 16, 1989, p. 6749.

Affiliated with

Also associated with

Rating

DNA sequence for the human dopamine receptor D.sub.4 and express does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA sequence for the human dopamine receptor D.sub.4 and express, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA sequence for the human dopamine receptor D.sub.4 and express will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-987142