DNA sequence encoding a selectin ligand

Details DNA sequence encoding a selectin ligand DNA sequence encoding a selectin ligand

1992-02-13

1994-04-19

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 691, 4353201, 4351723, 4352402, C12N 1512, C12N 510, C12N 1585

Patent

active

053046404

ABSTRACT:
The invention relates to glycoprotein ligands of selectins. The invention further relates to methods and means for preparing and to nucleic acids encoding these ligands. The invention further concerns a method of treating a symptom or condition associated with excessive binding of circulating leukocytes to endothelial cells by administering to a patient in need of such treatment a glycoprotein ligand of a selectin.

REFERENCES:
Gallatin et al., Nature 304, 30-34 (1983).
Stoolman and Rosen, J. Cell. Biol. 96, 722-729 (1983).
Tedder et al., J. Exp. Med. 170(1), 123-133 (1989).
Teder et al., J. Immunol. 144, 532-540 (1989).
Bevilacqua et al., Science 243:1160 (1989).
Bevilacqua et al., Proc. Natl. Acad. Sci. USA 84, 9238 (1989).
Berg et al., Immunol. Rev. 108, 5 (1989).
Bonfanti et al., Blood 73, 1109 (1989).
Bowen et al., J. Cell Biol. 109, 421 (1989).
Butcher, Am. J. Pathol. 136, 3 (1990).
Butcher, E. C., Curr. Top. Micro. Immunol. 128, 85 (1986).
Camerini et al., Nature 342(6245), 78 (1989).
Corral et al., Biochem. Biophys. Res. Commun. 172, 1349 (1990).
Duijvestijn and Hamann, Immunol. Today 10, 23 (1989).
Gallatin et al., Cell 44, 673 (1986).
Geng et al., Nature 343:757 (1990).
Geoffroy and Rosen, J. Cell. Biol. 109, 2463 (1989).
Goelz et al. Cell 63(6), 1349 (1990).
Hattori et al., J. Biol. Chem. 264(14), 7768 (1989).
Hession et al., Proc. Natl. Acad. Sci. USA 87(5), 1673 (1990).
Johnston et al., Cell 56, 1033 (1989).
Larsen et al. Cell 63, 467 (1990).
Lasky et al., Cell 56, 1045 (1989).
Lowe et al. Cell 63, 475 (1990).
McEver et al., J. Biol. Chem. 259, 9799 (1984).
Moore et al., J. Cell Biol. 112, 491 (1991).
Phillips et al. Science 250(4984), 1130 (1990).
Polley et al., Proc. Natl. Acad. Sci. USA 88, 6224 (1991).
Rosen et al., Science (Wash., D.C.) 228, 1005 (1985).
Rosen et al., J. Immunol. 142, 1895 (1989).
Siegelman et al., Science (Wash., D.C.) 243, 1165 (1989).
Siegelman et al., Proc. Natl. Acad. Sci. USA 5562 (1989).
Stoolman, Cell 56, 907 (1989).
Stoolman et al., J. Cell Biol. 99, 1535 (1984).
Stoolman et al., Blood 70, 1842 (1987).
Tiemeyer et al., Proc. Natl. Acad. Sci. USA 88(4), 1138-42 (1991).
True et al., J. Cell Biol. 11, 2757-2764 (1990).
Walz et al., Science 250(4984), 1132 (1990).
Watson et al., J. Cell Biol. 110, 2221 (1990).
Watson et al., Nature 349, 164-167 (1991).
Woodruff et al., Annu. Rev. Immunol. 5, 201 (1987).
Yednock and Rosen, Adv. Immunol. 44, 313 (1989).
Groves, R. W., et al., British J Derm. 124: 117-123 (1991).
Kameyama, A., et al., Carbohydrate Res. 209: c1-c4 (1991).
Picker, L., et al., Nature 349: 796-799 (1991).
Shimizu, Y., et al., Nature 349: 799-802 (1991).
von Adrian, U., et al., Proc. Natl. Acad. Sci. USA 88: 7538-7542 (1991).

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