Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1994-03-14
1996-05-28
Ziska, Suzanne E.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4351723, 4353201, 530350, 530381, 536 235, 536 232, C12N 1500, C12P 2106, C07K 1400, C07H 2104
Patent
active
055210708
ABSTRACT:
The present invention relates to a novel DNA sequence coding for factor IX or a similar protein, corresponding to a prosequence and to mature factor IX or the mature similar protein. According to the invention, position (-3) in the prosequence is occupied by a codon coding for valine, arginine, lysine, threonine or serine, and/or the first codon of the sequence coding for the mature protein codes for an alanine.
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Pavirani et al. Biotechnology 5:384, 1987.
Kurochi et al PNAS 79: 6461, 1982.
Bentley et al Cell 45: 343, 1986.
DiScipio et al Biochemistry 16(4): 698, 1977.
de la Salle et al Nature 316: 268, 1985.
Transgene S.A.
Ziska Suzanne E.
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