DNA sequence, and recombinant preparation of group 4 major...

Details DNA sequence, and recombinant preparation of group 4 major... DNA sequence, and recombinant preparation of group 4 major...

2011-05-03

2011-05-03

Rooney, Nora M (Department: 1644)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C424S275100, C514S002600, C530S350000

Reexamination Certificate

active

07935347

ABSTRACT:
The invention relates to the preparation of DNA sequences of group 4 major allergens from cereals. The invention also includes fragments, novel combinations of partial sequences and point mutations with hypoallergenic effects. The recombinant DNA molecules and the derived polypeptides, fragments, novel combinations of partial sequences and variants can be used for therapy of pollen-allergy diseases. The proteins produced by recombination can be applied to in-vitro and in-vivo diagnosis of pollen allergies.

REFERENCES:
patent: 5762943 (1998-06-01), Dolovich et al.
patent: 2005/0074464 (2005-04-01), Deweerd
patent: 2006/0177470 (2006-08-01), Fiebig et al.
patent: WO 03025009 (2003-03-01), None
patent: WO 2004000881 (2003-12-01), None
Tarzi et al. ‘Peptide immunotherapy for allergic disease.’Expert Opin. Biol. Therap. 3(4):617-626, 2003.
Gavrovic et al. ‘Microheterogeneity examination of grass group 4 allergens.’ Allergy 53(Suppl 43):27, 1998.
Stumvoll S et al: “Purification, Structural and Immunological Chacateriaztion of a Timothy Grass (Phleium Pratense) Pollen Allergen, PHL P 4, With Cross-Reactive Potential” Biological Chemistry, Bd. 383, Nor. 9, Sep. 2002, XP002260346.
Astwood J D et al: “Cloning and Expression Pattern of HOR V 9, the Group 9 Pollen Isoallergen From Barley” Gene: An International Journal of Genese and Genomes,Elsevier Science Publishers, Barking, GB, Bd. 182, Nr. 1-2 Dec. 5, 1996, XP004071930.
Rihs H P et al: “Polymerase Chain Reaction Based CDNA Clonong of Wheat Profilin: A Potential Plant Allergen” International Archives of Allergy and Immunology, Bd. 105, Jan. 1994, XP000604627.
Fahlbusch B et al: Detection and Quantification of Group 4 Allergens in Grass Pollen Extracts Using Monoclonal Antibodies: Clinical and Experimental Allergy, Blackwell Scientific Publications, London, GB, Bd. 28, Nr. 7, Jul. 1998, XP002260345.
Database EMBL′Online! 19. Nov. 2004, AJ862830.
Database EMBL 19. Nov. 2004, AJ862831.
Database ENBL 19. Nov. 2004, AJ862834.
Database ENBL 19. Nov. 2004, AJ862832.
Database EMBL 19. Nov. 2004, AJ862833.

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