DNA, polypeptides, monoclonal antibody and methods thereof

Details DNA, polypeptides, monoclonal antibody and methods thereof DNA, polypeptides, monoclonal antibody and methods thereof

1995-03-22

1998-07-07

Scheiner, Toni R.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 693, 4353201, 536 231, 536 235, C12N 1512, C12N 1500

Patent

active

057767270

ABSTRACT:
The present invention relates to a monclonal antibody capable of suppressing the motility of cancer cells, a polypeptide recognizable by said anti-cancer antibody and its fragment peptides which is capable of suppressing the motility of cancer cells. The present invention also relates to a production and a use for preventing the matastasis of cancer thereof.

REFERENCES:
Ayala, Modern Genetics, The Benjamin/Cumings Publishing Company, 1980, p. 45.
M. Miyake et al. "A Specific Cell Surface Glcoconjugate Controlling Cell Motility" Biochemistry, 30, (1991) pp. 3328-3334.
C. Boucheix, et al., "Molecular Cloning of the CD.sub.9 Antigen" J. Biol. Chem. (1991) pp. 117-122.
Pearlstein, et al. "Effect of Antiplatelet Antibody . . . " Cancer Research 44, pp. 3884-3887, (1984).
Yamada, et al. Cancer Research, 50(15), pp. 4485-4496 (1990).
Lanza, et al. Journal of Biological Chemistry, 266(16), pp. 10638-10645 (1991).
Miyake, et al., Journal of Experimental Medicine,174(6), pp. 1347-1354 (1991).

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