Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Patent
1994-07-22
1997-09-16
Hendricks, Keith D.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
536 232, 536 237, 530350, 4353201, 4352523, 43525233, 435325, C12N 912, C12N 1554
Patent
active
056680040
ABSTRACT:
The present invention is directed toward the 5 previously unknown genes, for subunits .delta., .delta.', .chi., .theta., and .psi., of the DNA polymerase III holoenzyme, and toward a unique man-made enzyme containing 5, preferably 6, protein subunits which shows the same activity as the naturally occurring 10 protein subunit DNA polymerase III holoenzyme.
REFERENCES:
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Studwell et al., "Processive Replication is Contingent on the Exonuclease Subunit of DNA Polymerase III Holoenzyme," The Journal of biological Chemistry 265(2):1171-78 (1990).
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Cornell Research Foundation Inc.
Hendricks Keith D.
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