DNA photocleavage using texaphyrins

Details DNA photocleavage using texaphyrins DNA photocleavage using texaphyrins

1995-06-06

1997-03-04

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514185, 514410, 424 96, 424 961, 435 6, 436 98, A61K 3140, A61K 31555

Patent

active

056079249

ABSTRACT:
Methods of cleavage of a polymer of deoxyribonucleic acid using photosensitive texaphyrins are disclosed. A preferred method of use is the site-specific cleavage of a polymer of deoxyribonucleic acid and a preferred texaphyrin is a derivatized texaphyrin having binding specificity, in particular, a texaphyrin covalently coupled to a site-directing molecule, preferably an oligonucleotide.

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Sessler, Jonathan L., "Texas-S

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