DNA molecules which encode the fimbrin protein of Haemophilus in

Details DNA molecules which encode the fimbrin protein of Haemophilus in DNA molecules which encode the fimbrin protein of Haemophilus in

1995-06-01

1998-06-16

Sidberry, Hazel F.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

536 221, 536 231, 536 237, 435 691, 435 693, 435 711, 435 712, 4353201, 4352523, 43525233, 4352528, 4242421, C12N 1531, C12N 1563, C07H 2100, A61K 39102

Patent

active

057666083

ABSTRACT:
It has been discovered that a vaccine comprised of fimbrin, a filamentous protein derived from the bacterial surface appendages of non-typable Haemophilus influenzae is useful in studying, preventing or reducing the severity of, otitis media. The gene sequence of the DNA coding for fimbrin and the amino acid sequence of fimbrin have also been determined. Vectors containing DNA coding for fimbrin have also been developed, and transformants have been prepared which contain such vectors and which express such DNA and provide a source of pure fimbrin.

REFERENCES:
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