Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-08-06
2000-06-06
Swartz, Rodney P.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
4241921, 4241901, 424 934, 435 724, 536 221, 536 2432, C07H 2104, C07H 1900, A61K 3900, G01N 3353
Patent
active
060720484
ABSTRACT:
The present invention relates to DNA molecules associated with conferring on Mycobacterium tuberculosis an ability to enter mammalian cells. The protein encoded by these DNA molecules are useful in vaccines to prevent infection by Mycobacterium tuberculosis, while the antibodies raised against this protein can be employed in passively immunizing those already infected by the organism. Both these proteins and antibodies may be utilized in diagnostic assays to detect Mycobacterium tuberculosis in tissue or bodily fluids. The protein of the present invention can be associated with various other therapeutic materials, for administration to mammals, particularly humans, to achieve uptake of those materials by such cells.
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Cornell Research Foundation Inc.
Swartz Rodney P.
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