DNA methyltransferase genomic sequences and antisense oligonucle

Details DNA methyltransferase genomic sequences and antisense oligonucle DNA methyltransferase genomic sequences and antisense oligonucle

1997-05-30

2000-02-01

Degen, Nancy

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 245, A61K 3170, C07H 2100

Patent

active

060203188

ABSTRACT:
The invention provides recombinant nucleic acids comprising nucleic acid sequences from the genomic DNA methyltransferase gene. The invention further provides sequence information for such nucleic acid sequences. In addition, the invention provides antisense oligonucleotides complementary to special regions of the genomic DNA methyltransferase gene or its RNA transcript. Finally, the invention provides methods for using such antisense oligonucleotides as analytical and diagnostic tools, as potentiators of transgenic plant and animal studies and gene therapy approaches, and as potential therapeutic agents.

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