DNA methylation gene from plants

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 241, 435 691, 435410, 435411, 435419, 800278, 800298, 800306, C12N 504, C12N 1529, C12N 1582, C12N 500, C07H 2104

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061537411

ABSTRACT:
A novel gene, DDM1, and its encoded protein are provided. The gene was isolated from a region of Arabidopsis thaliana chromosome 5. DDM1 appears to be part of the SWI2/SNF2 family of chromatin-remodeling proteins. Disruption of the gene results in DNA hypomethylation, among other phenotypes. The DDM1 gene defines a novel member of the DNA methylation system. Methods of using DDM1, and transgenic organisms comprising DDM1, are also provided.

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Richards, Trends in Genetics 13: 319-323, 1998.

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