DNA immunization against Chlamydia infection

Details DNA immunization against Chlamydia infection DNA immunization against Chlamydia infection

2006-06-20

2006-06-20

Swartz, Rodney P (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S085100, C424S093200, C424S185100, C530S300000, C530S350000, C536S022100, C536S023100, C536S023700

Reexamination Certificate

active

07063853

ABSTRACT:
Nucleic acid, including DNA, for immunization to generate a protective immune response in a host, including humans, to a major outer membrane protein of a strain ofChlamydia, preferably contains a nucleotide sequence encoding a fragment that generates antibodies that specifically react with MOMP and a promoter sequence operatively coupled to the first nucleotide sequence for expression of the MOMP fragment in the host. The non-replicating vector may be formulated with a pharmaceutically-acceptable carrier for in vivo administration to the host.

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