DNA-immobilized microspheres and a process for purifying a DNA-t

Details DNA-immobilized microspheres and a process for purifying a DNA-t DNA-immobilized microspheres and a process for purifying a DNA-t

1989-09-22

1992-06-16

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435 91, C07H 1700

Patent

active

051226006

ABSTRACT:
There are disclosed a DNA-immobilized microsphere comprising DNA chains having base sequences which bind a specific protein specifically, and a carrier having a particle size of not more than 50 .mu.m and not less than 0.01 .mu.m which does not adsorb any protein, said carrier and said DNA chains being bound to each other by a chemical bond, and a process for purifying a protein using said microsphere.

REFERENCES:
patent: 4806546 (1989-04-01), Carrico et al.
patent: 4806631 (1989-04-01), Carrico et al.
patent: 4912032 (1990-03-01), Hoffman et al.
Chem. Abstract 111:150064y, 1989.

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