DNA fragments coding for antigens specific to non-A non-B hepati

Details DNA fragments coding for antigens specific to non-A non-B hepati DNA fragments coding for antigens specific to non-A non-B hepati

1988-03-15

1991-07-16

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 91, 4351123, 4352351, 4352401, 43525231, 43525233, 4353201, 536 27, 530350, 935 18, 935 27, 935 31, 935 41, 935 56, 935 57, 935 65, 935 70, 935 73, 935 74, 935 81, C12P 2106, C12P 1934, C12N 1500, C12N 700, C12N 500, C12N 112, C12N 120, C12N 1551, C07H 1512, C07K 300

Patent

active

050325116

ABSTRACT:
Provided herein are a DNA fragment which contains a base sequence coding for a non-A non-B hepatitis-specific antigenic protein occurring in cells of the liver affected with non-A non-B hepatitis, an expression vector in which said DNA fragment is inserted into a cloning site present downstream from a promoter thereof, a transformant obtained by introducing said expression vector into a host, and a process for producing said antigenic protein which comprises providing said expression vector, transforming a host with said expression vector, culturing the transforming host and collecting the protein produced therein.

REFERENCES:
Toshitaka, A. et al., Chemical Abstracts 007 105 p. 527, Abstract No. 151110y (1986).
Molecular Cloning, A Laboratory Manual Cold Spring Harbor Laboratory, CSH, NY (1982) p. 8.
Robinson, W. S., Virology PCA II: Hepatitis b Virus, pp. 1384-1386.
Hakim Naturwissenschaften, vol. 73, pp. 45-47 (1986).
European Search Report; (No. 88 40 0790).
Chemical Abstracts, vol. 105, No. 17, Oct. 1986, p. 527, No. 151110y.
Biological Abstracts, vol. 80, 1985, No. 4871, J. I. Tohmatsu et al.
Proc. Natl. Acad. Sci. USA, vol. 80, Mar. 1983, pp. 1194-1198, Young et al.

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