DNA for expression of bovine growth hormone

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 694, 43525233, 935 44, 935 45, 536 2351, C12N 1518, C12N 1570

Patent

active

054895294

ABSTRACT:
High-level expression of bovine growth hormone is achieved using DNA encoding bovine growth hormone which, when transcribed, produces messenger RNA (mRNA) that at its 5' end is substantially free of secondary structure that is capable of interfering with translation of the mRNA.

REFERENCES:
patent: 3664925 (1972-05-01), Sonnenberg et al.
patent: 4342832 (1982-08-01), Goeddel et al.
patent: 4356270 (1982-10-01), Itakura
patent: 4443539 (1984-04-01), Fraser et al.
patent: 5254463 (1993-10-01), DeBoer et al.
Backman et al., "Maximizing Gene Expression on a Plasmid Using Recombination in Vitro", Cell, 13:65-71, (1978).
Bahramian, "How Bacterial Ribosomes Select Translation Initiation Sites", J. Theor. Biol., 84:103-118, (1980).
Cannistraro et al., "Escherichia coli lac Operator mRNA Affects Translation Initiation of .beta.-Galactosidase mRNA", Nature, 277:407-409, (1979).
Drlica, K., "Understanding DNA and Gene Cloning--A Guide for the Curious", John Wiley & Sons, (1984).
Dunn et al., "Mutations of Bacteriphage T7 that Affect Initiation of Synthesis of the Gene 0.3 Protein", Proc. Natl. Acad. Sci., USA, 75(6):2741-2745, (1978).
Edge et al., "Total Synthesis of a Human Leukocyte Interferon Gene", Nature, 292:756-762, (1981).
Gheysen et al., "Systematic Alteration of the Nucleotide Sequence Preceeding the Translation Initiation Codon and the Effects on Bacterial Expression of the Cloned SV40 Small-T Antigen Gene", Gene, 17:55-63, (1982).
Goeddel et al., "Direct Expression in Escherichia coli of a DNA Sequence Coding for Human Growth Hormone", Nature, 281(5732):544-548, (1979).
Goeddel et al., "Expression in Escherichia coli of Chemically Synthesized Genes for Human Insulin", Proc. Natl. Acad. Sci., USA, 76(1):106-110, (1979).
Gold et al., "Translational Initiation in Prokaryotes", Ann. Rev. Microbiol., 35:365-403 (1981).
Guarente et al., "A Technique for Expressing Eukaryotic Genes in Bacteria", Science, 209:1428-1430, (1980).
Hall et al., "A Role for mRNA Secondary Structure in the Control of Translation Initiation", Nature, 295:616-618. (1982).
Horn et al., "Synthesis of Oligonucleotides on Cellulose. Part II: Design and Synthetic Strategy to the Synthesis of 22 Oligodeoxynucleotides Coding for Gastric Inhibitory Polypeptide (GIP)", Nucleic Acids Research, 7:225-232, (1980).
Howard Florey Institute Annual Report, "Director's Review, Molecular Biology: New Initiatives", 23-24, 1980.
Hudson, et al., "Molecular Cloning and Characterization of cDNA Sequences Coding for Rat Relaxin", Nature, 291:127-131, (1981).
Hudson et al., "Genomic Structure of the Large RNA Segment of Infectious Bursal Disease Virus", Nuc. Acids Res., 14(12):5001-5013, (1986).
Iserentant et al., "Secondary Structure of mRNA and Efficiency of Translation Initiation", Gene, 9:1-12, (1980).
Itakura et al., "Expression in Escherichia coli of a Chemically Synthesized Gene for the Hormone Somatostatin", Science, 198:1056-1063, (1977).
Johnston et al., "Model for Regulation of the Histidine Operon of Salmonella", Proc. Natl. Acad. Sci. USA, 77(1):508-512, (1980).
Keshet et al., "Cloning of Bovine Growth Hormone Gene and Its Expression in Bacteria", Nuc. Acids Res., 9(1):19-30, (1981).
Klambt et al., "Computer Programs for Studying Conformations in Ribonucleic Acids", J. Theor. Biol., 58:319-324 (1976).
Korobko et al., "Chemical-Enzymatic Synthesis and Cloning of an Artificial Structural Gene for Bradykinin", Bioorganicheskaya Khimiya, 5:1802-15, (1979).
Kozak, "Mechanism of mRNA Recognition by Eukaryotic Ribosomes During Initiation of Protein Synthesis", Current Topics in Microbio & Immunology, 93:81-123, (1981).
Kozak, M., "Influence of mRNA Secondary Structure on Binding and Migration of 40S Ribosomal Subunits", Cell, 19:79-90, (1980).
Kumarev et al., "Molecular Cloning of Synthetic Angiotensin 1 Gene in Escherichia coli", FEBS Letters, 114(2):273-277, (1980).
McIntyre et al., "Selection of a cDNA Clone Which Contains the Complete Coding Sequence for the Mature Form of Ornithine Traanscarbamylase from Rat Liver: Expression of the Cloned Protein in Escherichia coli", Eur. J. Biochem., 143:183-186, (1984).
Mercereau-Puijalon et al. "Expression of Eukaryotic Viral And Cellular Genes", Pettersson et al. ED. 295-303, (1981).
Miller et al., "Molecular Cloning of DNA Complementary to Bovine Growth Hormone mRNA", J. Biol. Chem., 255(16):7521-7524, (1980).
Miller et al., "Molecular Cloning of Gene Sequences Coding for Vobine Growth Hormone and Prolactin", Pediatric Res., 14:335, (1980).
Min Jou et al., "Nucleotide Sequence of the Gene Coding for the Bacteriophage MS2 Coat Protein", Nature, 237:83-88, (1972).
Miozzari, G., "Strategies for Obtaining Expression of Peptide Hormones in E. coli*", Recombinant DNA Tech. Bulletin, 57-67, (1980).
Oxender et al., "Attenuation in the Escherichi coli Tryptophan Operon: Role of RNA Secondary Structure Involving the Trytophan Codon Region", Proc. Natl. Acad. Sci. USA, 76(1):5524-5528, (1979).
Queen et al., "Differential Translation Efficiency Explains Discoordinate Expression of the Galatose Operon", Cell, 25:241-249, (1981).
Roberts, T. M., "A lac Promoter System for the Overexpression of Prokaryotic and Eukaryotic Genes in E. coli", Promoters, Structure and Function, 452-461, (1982).
Schoner et al., "Role of mRNA Translational Efficiency in Bovine Growth Hormone Expression in Escherichia coli", Proc. Natl. Acad. Sci. USA, 81:5403-5407, (1984).
Schwartz et al., "Mutations that Affect lamB Gene Expression at a Posttranscriptional Level", Proc. Natl. Acad. Sci. USA, 78(5):2937-2941, (1981).
Seeburg et al., "Efficient Bacterial Expression of Bovine and Porcine Growth Hormones", DNA 2:37-45 (1983).
Shepard et al., "Increased Synthesis in E. coli of Fibroblast and Leukocyte Interferons Through Alterations in Ribosome Binding Sites", DNA, 1(2):125-131, (1982).
Shine et al., "Expression of Cloned .beta.-endorphin gene sequences by Escherichia coli" Nature, 285,456-461 (1980).
Singer et al., "Analysis in Vivo of Translational Mutants of the rIIB Cistron of Bacteriophage T4", J. Mol. Biol., 149:405-432, (1981).
Staden, R., "Further Procedures for Sequences Analysis by Computer", Nuc. Acids Res., 5:1013-1015.
Steege, D. A., "5'-Terminal Nucleotide Sequence of Escherichia coli Lactose Repressor mRNA: Features of Translational Initiation and Reinitiation Sites", Proc. Natl. Acad. Sci., USA, 74(10):4163-4167, (1977).
Steitz, "Genetic Signals and Nucleotide Sequence in Messenger RNA", Biological Regulation and Development, 1:349-399, (1979).
Steitz, Nature, "Polypeptide Chain Initiation: Nucleotide Sequences of the Three Ribosomal Binding Sites in Bacteriophage R17 RNA", 224:957-964, (1969).
Steitz et al., "How Ribosomes Select Initiator Regions in mRNA: Base Pair Formation Between the 3' Terminus of 16S rRNA and mRNA During Initiation of Protein Synthesis in Escherichia coli", Proc. Natl. Acad. Sci. USA, 72:4734-4738, (1975).
Steitz, "Ribosome Recognition of Initiator Regions in the RNA Bacteriophage Genome", RNA Phages, Zinder (ED.), 319-352, (1975).
Sverdlov et al., "Cloning and Expression of a Synthetic Leucine-Enkephalin", Bioorganicheskaya Khimiya 5:1112-15, (1970).
Talkad et al., "Evidence for Variable Rates of Ribosome Movement in Escherichia coli", J. Mol. Biol., 104:299-303, (1976).
Tinoco, "Improved Estimation of Secondary Structure in Ribonucleic Acids", New Biology, 246:40-41, (1973).
Watson, J. D., "The Wobble in the Anticodon", Molecular Biology of the Gene, 357, 374 and 375 (1976).
Watson, J. D., "The Replication of DNA", Molecular Biology of the Gene, 208-211, (1976).
Wetzel, R., "Applications of Recombinant DNA Technology", American Scientist, 68(6):664-675, (1980).
Wetzel et al., "Production of Biologically Active N.alpha.-Desacetylthymosin .alpha..sub.1 in Escherichia coli Through Expression of a Chemically Synthesized Gene", Biochemistry, 19:6096-6104, (1980).
Wieringa et al., "Translation in vivo and in vitro of mRNAs Coding for Vitellogenin, Serum Albumin and Very-Low-Density Lipoprotein II from Chicken Liver", Eur. J. Biochem, 114:635-641, (1981).
Zucker et al., "Optimal Computer

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

DNA for expression of bovine growth hormone does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA for expression of bovine growth hormone, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA for expression of bovine growth hormone will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2174614

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.