Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1992-12-28
1996-11-12
Draper, Garnette D.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 43525233, 935 51, 536 235, C07K 1453, C12N 121, C12N 1527
Patent
active
055739300
ABSTRACT:
A colony stimulating factor, CSF-1, is a lymphokine useful in regulating the immune system is a lymphokine useful in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein. Both "long" and "short" forms of this protein and muteins corresponding to the cDNA-encoded forms are disclosed.
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Coyne Mazie Y.
Halenbeck Robert F.
Kawasaki Ernest S.
Koths Kirston E.
Ladner Martha B.
Blackburn Robert P.
Cetus Oncology Corporation
Draper Garnette D.
McGarrigle Philip L.
Pochopien Donald J.
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