DNA encoding variants of human corticosteroid binding globulin

Details DNA encoding variants of human corticosteroid binding globulin DNA encoding variants of human corticosteroid binding globulin

1992-12-16

1995-07-11

Wax, Robert A.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

536 235, 530386, C12N 510, C12N 1500

Patent

active

054320801

ABSTRACT:
A novel steroid-binding variant of human corticosteroid binding globulin in which one or more of the glycosylation sites, other than the glycosylation site at amino acid position 238, has been functionally disrupted is complexed with an anti-inflammatory ligand in the treatment of inflammation in mammals.

REFERENCES:
patent: 4997814 (1991-03-01), Hammond
patent: 5086039 (1992-02-01), Hammond
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