DNA encoding tumor necrosis related receptor TR7

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 695, 4352523, 4353201, 536 235, 536 243, C12N 1509, C12N 1500

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active

060134763

ABSTRACT:
TR7 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing TR7 polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, arthritis, septicemia, autoimmune diseases (such as inflammatory bowel disease and psoriasis), transplant rejection, graft versus host disease, infection, stroke, ischemia, acute respiratory disease syndrome, restenosis, brain injury, AIDS, bone diseases, cancer (such as lymphoproliferative disorders), atherosclerosis, and Alzheimers disease, among others and diagnostic assays for such conditions.

REFERENCES:
Kwon et al.; "A newly-identified member of the tumor necrosis factor receptor superfamily", Journal of Allergy and Clinical Immunology, vol. 99 (1), p. S467 (1997). Abstract.
Fujiwara et al.; "Unpublished", Database EMBL, XP002072603, entryname HS073E08B, Aug. 27, 1995. Abstract.
Copy of Partial European Search Report.
STN Search Print Out of TNF-Receptor Related Products.
Accession # AA351536.
Accession # AA155873.
Accession # D59902.
Accession # AA357321.
Accession # AA374471.
Accession #N49208.
Accession # H44577.
Accession # H44234.
Accession # AA382042.
EST # 1502886.
EST # 843791.
EST # 2051015.

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