DNA encoding Toxoplasma gondii rDGP5p protein

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S320100

Reexamination Certificate

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07544789

ABSTRACT:
Recombinant proteins have been developed for the detection ofToxoplasma gondiioocyst proteins for example in biological fluids. Isolated DNA sequences which encode these proteins have also been developed. The DNA sequences may be inserted into recombinant DNA molecules such as cloning vectors or expression vectors for the transformation of cells and the production of the proteins.

REFERENCES:
Lecordier et al (1993), Mol. and Biochem. Parasitol. 59: 143-154.
Lecordier, Laurence et al., “Molecular structure ofToxoplasma gondiidense granule antigen(GRA 5) associated with the parasitophorous vacuole membrane,” Molecular and Biochemical Parasitology, 1993, vol. 59, pp. 143-145.
Lecordier, Laurence et al., “Molecular structure ofToxoplasma gondiidense granule antigen(GRA 5) associated with the parasitophorous vacuole membrane,” Molecular and Biochemical Parasitology, 1993, vol. 59, pp. 143-154.
Gamble, H. Ray et al., “Use of Recombinant Antigens for Detection ofToxoplasma gondiiInfection in Swine,”The Journal of Parasitology, Jun. 2000, vol. 86, No. 3, pp. 459-462.
NCCLS, “Clinical Use and Interpretation of Serologic Tests forToxoplasma gondii; Approved Guideline,” M36-A, vol. 24, No. 6, pp, 2004.

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