DNA encoding the recombinant 40 kDA Dermatophagoides farinae all

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4241841, 4241851, 4242751, 4351723, 435 691, 4352523, 4353201, 514 2, 536 231, 536 234, 536 236, A61K 3935, A61K 3936, C12N 1529, C12N 1562

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054057582

ABSTRACT:
The present invention is directed to a recombinant mite allergen obtainable by expression of a mite-body-derived gene, a gene which codes for said allergen, a mite allergen fragment, a polypeptide having an epitope contained in said allergen, an expression vector capable of expressing the gene, a bacterium, yeast or mammalian cell transformed with said expression vector, a method for producing said allergen, and a pharmaceutical composition or a diagnostic reagent for the treatment of mite allergic diseases.

REFERENCES:
Chua et al, Int. Arch. Allergy Immunol 1990:91: 1:118-123.
Chua et al, Int. Arch. Allergy Appl. Immunol 1990:91:124-129.
Thomas et al, Int. Archs. Allergy appl. Immun. 85 127-129 (1988).
Yuuki et al, Agric, Biol. Chem., 55 (5) 1233-1238, 1991.
Tovey et al, J. Exp. Med. vol. 170, Oct. 1989 1457-1462.
Chua et al, J. Exp. Med, vol. 167, Jan. 1988 pp. 175-182.
Suko et al, Jpn, J. Allergol, 39, (6), 557-561, 1990.

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