DNA encoding the prostate-specific membrane antigen-like...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

Reexamination Certificate

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C435S252300, C435S320100, C435S348000, C435S410000, C536S023100, C536S023500, C530S350000

Reexamination Certificate

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06897062

ABSTRACT:
The present invention discloses a new gene, termed PSMA-like, that is very similar to the prostate-specific membrane antigen (PSMA) gene and cross-reacts with current detection methods for PSMA. The present invention also provides for a method of distinguishing the PSMA and PSMA-like mRNAs and/or proteins for diagnostic and therapeutic strategies that desire specific targeting of either the PSMA or PSMA-like gene.

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Bowie et al (Science, 1990, 257 : 1306-1310).*
Burgess et al, (Journal of Cell Biology, 1990, 11:2129-2138).*
Lazar et al. Molecular and Cell Biology, 1988, 8: 1247-1252.*
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Verma (Sep. 1997, Nature, vol. 389, pp. 239-242).*
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Su SL et al, 1995, Cancer Res, 55: 1441-1443.*
MPSRCH search report, 2004, us-09-973-382c-1.oli.mi, p.7.

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