DNA encoding the human synapsin III gene and uses thereof

Details DNA encoding the human synapsin III gene and uses thereof DNA encoding the human synapsin III gene and uses thereof

1997-08-06

2000-03-21

Duffy, Patricia A.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

43525231, 43525233, 43525234, 43525235, 4353201, 435348, 435354, 435358, 435365, 435366, 435411, 536 235, 536 2431, C12N 1585, C12N 121, C12N 1563, C07H 2104

Patent

active

060401680

ABSTRACT:
A new synapsin protein, designated synapsin III, its amino acid sequence, and its human gene have been isolated and characterized. The synapsin III gene is located on human chromosome 22, in the vicinity of a region previously identified as a susceptibility locus for schizophrenia. The information and experimental tools provided by this discovery can be used to generate new therapeutic agents or diagnostic assays for this new protein, its associated mRNA or its associated genomic DNA. Due to its role in neurotransmission and synaptogenesis, this synapsin III is associated with the symptoms of psychiatric diseases, especially schizophrenia.

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