DNA encoding subunits of a high affinity GM-CSF receptor

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 691, 435 695, 530350, 530351, C07H 1700, C12P 2106, C07K 1300, C07K 1500

Patent

active

051129612

ABSTRACT:
Nucleic acids encoding the .beta. chain of the human granulocyte-macrophage colony stimulating factor (GM-CSF) receptor, as well as the .beta. chain itself, are provided. The .beta. chain may be expressed with the .alpha. chain in cellular hosts to form compositions useful in screening agonists and antagonists of human GM-CSF.

REFERENCES:
Gearing et al. (1989) Expression Cloning of a Receptor for Human Granulocyte-Macrophage CSF, EMBO 8, 3667-3676.

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