DNA encoding streptococcus pneumoniae trigger factor polypeptide

Details DNA encoding streptococcus pneumoniae trigger factor polypeptide DNA encoding streptococcus pneumoniae trigger factor polypeptide

1998-11-20

2000-08-08

Navarro, Mark

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4352523, 4353201, 435325, 536 237, C12N 1509, C12N 120, C12N 1500, C12N 502, C07H 2104

Patent

active

061000698

ABSTRACT:
The invention provides tig polypeptides and polynucleotides encoding tig polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tig polypeptides to screen for antibacterial compounds.

REFERENCES:
Smith, Elem. of Molec.Neurobio. 2nd ed. p. 74-82, 1996.
Darnell et al, Molec.Cell Bio. p. 400-401, 1986.
Brakhage, et al., GenBank Submission, Accession No. Z75208, Direct Submission, Apr. 16, 1997.
Gothel, et al., "An Internal FK506-binding Domain is the Catalytic Core of the Prolyl Isomerase Activity Associated with the Bacillus subtilis Trigger Factor", Eur. J. Biochem., vol. 244, pp. 59-65, (1997).
Hesterkamp, et al., "Identification of the Prolyl Isomerase Domain of Escherichia coli Trigger Factor", FEBS Letters, vol. 385, pp. 67-71, (1996).

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