DNA encoding rat and human protein kinase C

Details DNA encoding rat and human protein kinase C DNA encoding rat and human protein kinase C

1992-09-16

1994-06-28

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435 691, 4352402, 4352523, 43525233, 536 232, C12N 1554, C12N 121, C12N 510, C12P 2102

Patent

active

053246519

ABSTRACT:
Human protein kinase C and rat protein kinase C, recombinant DNA containing DNA sequence coding for kinase C, a transformant transformed with a vector containing the above recombinant DNA, and the production method of human or rat kinase C by cultivating the transformant are disclosed.
Kinase C is useful as reagent for studying cellular signal transduction mechanism, as diagnostic and inspection agent for disease, for example tumor, resulting from the trouble of cellular signal transduction mechanism, and as screening agent for a preventive agent or medicine to the disease.

REFERENCES:
Knopf, Cell, 46:491-502 (1986).
Suggs, et al., PNAS, 78:6613-6617 (1981).
Kikkawa, et al., BBRC, 135:636-643 (1986).
Ballister, et al., J. Biol. Chem., 260:15194-15199 (1985).
Ohno, et al., Biotrend, 1-2:22-27.
Ono, et al., Gan Idenshi Kenkyu Saikin No. Shimpo, Igakusha, Ed. at pp. 138-145 (1991).
Kikkawa, et al., Methods in Enzymology, 99:288-298 (1983).
Nishizuka, Nature, 308:693 (1984).
Nishikuza et al., Science, 233:305 (1986).
Parker, et al., Science, 233:853 (1986).
Coussens, et al., Science, 233:859 (1986).
Ohno, et al., Nature, 325:161 (1987).
Housey, et al., Journal of Cellular Biochemistry, Suppl. 10C:107 (1986).
Ullrich, et al., Cold Spring Harbor Symposia on Quantitative Biology, vol. L1:713 (1986).
Ono, et al., FEBS Letters, vol. 203:111 (1986).
Makowske, et al., The Journal of Biological Chemistry, vol. 26:13389 (1986).
Ono, et al., FEBS Letters, vol. 206:347 (1986).
Housey, et al., PNAS, 84:1065 (1987).
Ono, et al., Science, 236:1116 (1987).
Kikkawa, et al., FEBS Letters, 217:227 (1987).
Coussens, et al., DNA, 6:389 (1987).
Margolin, P.; in Escherichia coli and Salmonella typhimurium, Cellular and Molecular Biology, Neidhardt, F. (Ed.), Amer. Soc. for Microbiol., Washington, D.C., (1987), pp. 1154-1168.
Kikkawa, U. et al.; Ann. Rev. Biochem., 58:31-44 (1988).
Kubo, K. et al.; FEB Letters, 223:138-142 (Oct. 1987).
Perkins, A. S. et al.; Mol. Cell. Biol., 3:1123-1132 (1983).
Knopf, J. L. et al.; Cell, 46:491-502 (Aug. 1986).
Coussens, L. et al.; Science, 233:859-866 (1986).
Housey, G. M. et al.; Proc. Natl. Acad. Sci. USA, 84:1065-1069 (Feb. 1987).

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